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Combined steroid therapy in sudden hearing loss

Phase 1
Conditions
Idiopathic Sudden Sensorineural Hearing Loss
Therapeutic area: Diseases [C] - Ear, nose and throat diseases [C09]
Registration Number
EUCTR2017-000658-20-HU
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Authorised-recruitment may be ongoing or finished
Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Unilateral sensorineural hearing loss (30 dB at three consecutive frequencies) within 72 hours, older than 18 years old
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 50
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 50

Exclusion Criteria

Pregnant or breast-feed

Study & Design

Study Type
Interventional clinical trial of medicinal product
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Main Objective: The main objective of the trial is to compare hearing result in ISSHL patient who have recieved combined steroid therapy with systemic steroid therapy alone;Secondary Objective: Not applicable;Primary end point(s): Our goal is to prove that hearing recovery after ISSNHL is significantly better in the combination therapy group than in the only systemic therapy group.;Timepoint(s) of evaluation of this end point: 2 years
Secondary Outcome Measures
NameTimeMethod
Secondary end point(s): No further side effects in case of intratympanic steroid application;Timepoint(s) of evaluation of this end point: 2 years
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