JPRN-UMIN000009003已完成未知
Analysis of genetic polymorphism relating to interstitial lung disease events in with advanced pancreatic cancer patients receiving gemcitabine plus erlotinib - Analysis of genetic polymorphism relating to interstitial lung disease events in with advanced pancreatic cancer patients receiving gemcitabine plus erlotinib
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 入组人数
- 50
研究概览
简要总结
The combination of HLA-B15:01 and DRB115:01 suggested to be associated with ILD in Japanese patients with advanced pancreatic cancer receiving gemcitabine plus erlotinib.
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 20years-old 至 80years-old（—）
- 性别
- All
入选标准
- 未提供
排除标准
- •1)Pregnancy,lactational woman.Man hope who's partner's pregnancy. 2)Patients who have a concurrent or previous interstitial lung disease, idiopathic pulmonary fibrosis, pneumoconiosis,drug-induced pneumonia. 3)Patients who have a concurrent or previous pulmonary emphysema or chronic obstructive pulmonary disease. 4)Patients who are after resection one lung. 5)Patients who have a history of radiation to the chest. 6)Patients who have received gemcitabine within 3 months. 7)Patients who had previously been exposed to EGFR inhibitor. 8)Patients who received transfusion within 4 weeks before registry. 9)Patients who have the follows digestive tract damage. patients who can't take a pill. patients wfo have active ulcer. 10)Patients who have clinically problematical oculus disease(serious xerosis,keratoconjunctivitis sicca, keratitis). 11)Patients who have symptomatic metastatic brain tumor. 12)Patients who have active bacterium or fungus infections. 13)Patients who have a concurrent clinically problematical heart disease(uncontroled hypertension,unstable angina, congestive heart failure,severe arrhythmia,myocarcial infraction within 12 months before registry). 14)Patients who have a current uncontroled diabetes mellitus. 15)Patients who have massive humor pool or edema. 16)Patiens who have previous severe drug-induced allergy. 17)In cases of doctor judged inappropriate for this protocol.
研究者
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