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The effectiveness of intrauterine insemination (IUI) in subfertile couples with an isolated cervical factor: a randomised controlled trial

Completed
Conditions
Subfertility
Pregnancy and Childbirth
Registration Number
ISRCTN63217062
Lead Sponsor
Academic Medical Center Amsterdam (The Netherlands)
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Female
Target Recruitment
100
Inclusion Criteria

Couples with a cervical factor and otherwise no factors that reduced their fertility i.e. a prognosis for a treatment independent ongoing pregnancy in the next year higher than 30%. A cervical factor was diagnosed by a well-timed, non-progressive post-coital test (PCT) with normal semen parameters.

Exclusion Criteria

All other subfertile couples

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
The primary endpoint was ongoing pregnancy within six months. Ongoing pregnancy was defined as the presence of foetal cardiac activity at transvaginal sonography at a gestational age of at least 12 weeks.
Secondary Outcome Measures
NameTimeMethod
Secondary endpoints were total number of clinical pregnancies, miscarriages and multiple pregnancies.
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