The effects of eccentric overload resistance exercise training on muscle mass and strength for people with prostate cancer and chemical castratio

Not Applicable

Recruiting

• Conditions: Prostate cancer; Lean muscle mass decline; Cancer - Prostate; Musculoskeletal - Other muscular and skeletal disorders

• Registration Number: ACTRN12621000690853
• Lead Sponsor: Edith Cowan University

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2021-06-07
• Last Update Posted: 5 December 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: Male
• Target Recruitment: 14

Inclusion Criteria

Men with prostate cancer undergoing androgen deprivation therapy

Exclusion Criteria

Exclusion criteria will include absence of histologically documented prostate cancer; having undergone chemotherapy within the previous 6 months; not receiving ADT in the previous 3 months; not scheduled to receive ADT for the subsequent 4 months; any metastatic disease; any musculoskeletal, cardiovascular, or neurological disorder that could inhibit them from exercising; inability or unwillingness to undertake upper- and lower-limb exercise training; unwillingness or inability (lactose intolerance) to consume whey protein supplementation after each exercise session; and having performed resistance training in the previous 6 months.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Whole-body lean mass (assessed through dual energy X-ray absorptiometry)[1. Baseline<br>2. 4 days post-intervention completion];Muscle strength (Composite; maximum strength test for each exercise that will be performed during the training: abdominal crunch, seated row, chest press, lat pulldown, shoulder press, and leg press)[1. Baseline<br>2. 4 days post-intervention completion];Knee extensor muscle area (composite; assessed through ultrasonography)[1. Baseline<br>2. 4 days post-intervention completion]