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Meridian Activation Remedy System for Parkinson's Disease — A Randomized Controlled Trial

Not Applicable
Recruiting
Conditions
Diseases of the nervous system
Registration Number
KCT0006646
Lead Sponsor
Daejeon Korean Medicine Hospital of Daejeon University
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
All
Target Recruitment
88
Inclusion Criteria

1) 45 to 75 years of age
2) Patients with PD, diagnosed according to the UK Parkinson’s Diseases Society Brain Bank Criteria
3) Hoehn and Yahr scale stage I to III
4) Patients who have voluntarily decided to participate in the clinical study and signed the informed consent form

Exclusion Criteria

1) Clinically unstable patients (e.g., elevated aspartate transaminase(AST) or alanine aminotransferase(ALT) more than three-fold the upper limit of normal in the research institute's laboratory, heart failure, respiratory failure, etc.)
2) Patients who are planning to undergo deep brain stimulation within the study period
3) Pregnant or lactating women
4) Patients with MMSE-K(Mini-Mental State Exam) score of 18 or less
5) If there has been a change in the dosage of antiparkinsonian drugs (e.g., L-dopa, COMT inhibitor, Dopamine agonist, MAO-B inhibitor, etc.) according to a doctor's prescription within the last 4 weeks prior to enrollment
6) Patients who are receiving manual therapy, exercise therapy, or rehabilitation therapy for Parkinson's disease according to a doctor's prescription within the last 4 weeks prior to enrollment, or are planning to receive such therapy within the study period
7) Patients who are not suitable for participation in this clinical study according to the judgment of the researcher

Study & Design

Study Type
Interventional Study
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
MDS-UPDRS(Movement Disorder Society Unified Parkinson’s Disease Rating Scale) Part ?
Secondary Outcome Measures
NameTimeMethod
MDS-UPDRS(Movement Disorder Society Unified Parkinson’s Disease Rating Scale) Part ?;IPAQ(International Physical Activity Questionnarie Short Form);Parkinson Self Questionnaire;PDSS(Parkinson’s disease Sleep Scale);TUG(Timed up and go test);GAITRite(GAITRite Electronic Walkway Platinum);fNIRS(Functional near-infrared spectroscopy);Smartband outcomes(number of steps per day, daily sleep hours, sleep pattern, etc);Iris imaging 1;Iris imaging 2;MDS-UPDRS(Movement Disorder Society Unified Parkinson’s Disease Rating Scale);Gut microbiome test
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