Effect of Pranayama on movement of chest wall, respiratory muscle and lung function in patients with lung disease

Recruiting

• Registration Number: CTRI/2023/01/048897
• Lead Sponsor: MGM School of Physiotherapy, MGM Institute of Health Sciences

Brief Summary

The objective of the study is to evaluate the influence of Pranayama breathing techniques on thoracic cage biomechanics, respiratory muscle activity, and lung function in patients with chronic respiratory disease. It is a randomized controlled trial where two groups of patients with chronic respiratory disease will be undergoing rehabilitation for a period of 12 weeks. The control group will be receiving conventional pulmonary rehabilitation and the experimental group will receive additional Pranayam breathing techniques. The patients will be assessed for thoracic kinematic using reflective markers and the motion of the chest will be evaluated by the Vicon 3D motion capture system, respiratory muscle activity will be assessed by surface EMG, and pulmonary lung functions will measure the forced vital capacity, forced expiratory volume, at 1-second maximum inspiratory pressure, maximum expiratory and cardiovascular endurance will be recorded by six-minute walk test. The patient will be assessed at the beginning and end of the 12-week intervention. Knowledge gained from the study will help the prescription of evidence-based pulmonary rehabilitation including Pranayama to improve chest mobility, respiratory muscle activity, and lung function.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-16
• Last Update Posted: 2023-08-30

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 52

Inclusion Criteria

i.Any stable chronic respiratory diseases over 4 weeks (ICD 10 Classification- Bronchitis (J40-42), Emphysema (J43), other COPD (J44), Asthma (J45-46), Bronchiectasis (J47), Pneumoconiosis (J60-70), Adult respiratory distress syndrome (J80), Idiopathic Pulmonary Fibrosis (J84) ii.Age group of 18- 75 years both male and female iii.Mild to severe obstructions with GOLD grade 1-3, post bronchodilator FEV1/FVC <0.7, FEV1 30- 80% for obstructive conditions and FVC<80% with FEV1/FVC >0.7 for restrictive conditions.

Exclusion Criteria

i.Recent exacerbation of the disease ii.Associated cardiac, psychological, neurological disorders iii.BMI >35 kg/m2 iv.Thoracic cage abnormalities like scoliosis, kyphosis, recent trauma, fractures of ribs.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
•Respiratory muscle activity assessment using surface EMG	Pre intervention, at the 6th week of intervention, at the 12th week of intervention
•Pulmonary lung functions will measure the forced vital capacity, forced expiratory volume, at 1 second maximum inspiratory pressure, maximum expiratory	Pre intervention, at the 6th week of intervention, at the 12th week of intervention
•Kinematics of the thorax using 3D motion-capture system	Pre intervention, at the 6th week of intervention, at the 12th week of intervention
•Assess the cardiovascular endurance using six-minute walk test	Pre intervention, at the 6th week of intervention, at the 12th week of intervention

Trial Locations

Locations (2)

MGM Centre of Human Movement Science, MGM School of Physiotherapy, MGM Institute of Health Sciences; 🇮🇳 Raigarh, MAHARASHTRA, India

MGM School of Physiotherapy, MGM Institute of Health Sciences; 🇮🇳 Raigarh, MAHARASHTRA, India

MGM Centre of Human Movement Science, MGM School of Physiotherapy, MGM Institute of Health Sciences

🇮🇳Raigarh, MAHARASHTRA, India

Dr Rajani Mullerpatan

Principal investigator

9920048476

rajani.kanade@gmail.com