Biochemical analysis of tear composition in dry eye patients
Not Applicable
- Conditions
- Dry eye
- Registration Number
- JPRN-UMIN000025752
- Lead Sponsor
- Department of Ophthalmology, National Hospital Organization Tokyo Medical Center
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
Not provided
Exclusion Criteria
1) Complication of anterior disease(blepharitis, lagophthalmos, blepharospasm and iritis) other than dry eye ( patients with past history of the above disease are included). 2) Patients who were assessed as inadequate.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tears are colloected by Schirmer test strips from the dry eye patints, which are clinically performed. After the elution of tear protein and lipid, total protein and lactoferrinm lipocalin, lysozyme and secretory IgA are measured. And cytokines, phospholipase A2, lipids are fractioned and quantified.
- Secondary Outcome Measures
Name Time Method