Efficacy of parietal continous infiltration of local anesthesic on diaphragmatic function after upper abdominal surgery through a subcostal incisio

• Conditions: Diaphragmatic function after upper abdominal surgery through a subcostal incision; MedDRA version: 18.0Level: HLTClassification code 10012706Term: Diaphragmatic disordersSystem Organ Class: 100000004855; Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Anesthesia and Analgesia [E03]

• Registration Number: EUCTR2013-002184-26-FR
• Lead Sponsor: CHU de Rouen

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2015-09-28
• Last Update Posted: 28 September 2015

Recruitment & Eligibility

• Status: Authorised-recruitment may be ongoing or finished
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

- Upper abdominal surgery through subcostal incision
- More than 18 years old , less tha 80 years old
- ASA between 1 and 3
- Effective contraception for more than 3 months in women of childbearing age
- Patients signed an informed consent
- Affiliation to a social security regimen

Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range 60
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range 28

Exclusion Criteria

- BMI more than 30 kg/m2
- Functionnal state of total dependence
- Nasal obstruction during inclusion
- Preoperative treatment with morphin
- Need for a postoperative nasogastric tube
- Difficulty to understand the use of the PCA and/or the sniff-test
- Impossibility to place the catheter in preperitoneal position
- Pregnant women or breasting women
- Patients under guardianship
- Contraindication to use of ropivacaine
- Inclusion in another clinical trial

Study & Design

• Study Type: Interventional clinical trial of medicinal product
• Study Design: Not specified