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临床试验/NCT07089004
NCT07089004已完成不适用

Co-relation of Hypomagnesemia With Clinical Outcomes in Critically Ill Patients Admitted to a Tertiary Care ICU in Bangladesh

Bangladesh Bioscience Research Group1 个研究点 分布在 1 个国家目标入组 112 人开始时间: 2024年6月1日最近更新:

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
112
试验地点
1
主要终点
Association of Hypomagnesemia with ICU Mortality

研究概览

简要总结

Magnesium is an essential electrolyte involved in numerous physiological processes, including maintaining cellular integrity, regulating muscle tone, supporting cardiovascular function, and modulating immune responses. Despite its critical role, magnesium is often overlooked in clinical practice, earning it the title of the "forgotten electrolyte." Hypomagnesemia, defined as serum magnesium levels below 1.5 mEq/L, has been associated with adverse clinical outcomes such as increased mortality, prolonged ICU stays, and higher requirements for mechanical ventilation. Critically ill patients are particularly vulnerable to hypomagnesemia due to various underlying conditions, gastrointestinal losses, and renal complications. However, limited data are available from Bangladesh on the burden and clinical impact of hypomagnesemia in ICU settings. This study aims to assess the correlation between hypomagnesemia and clinical outcomes, including length of ICU stay, need for mechanical ventilation, and mortality among critically ill patients in a tertiary care ICU in Bangladesh.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients aged 18 years and above.
  • Patients admitted to the Intensive Care Unit (ICU).
  • Patients who have serum magnesium levels measured within 24 hours of ICU admission.

排除标准

  • Patients with known end-stage renal disease on dialysis.
  • Patients with a history of magnesium supplementation prior to ICU admission.
  • Pregnant women.
  • Patients with incomplete medical records or unavailable laboratory data.

结局指标

主要结局

Association of Hypomagnesemia with ICU Mortality

时间窗: From the date of ICU admission until the date of ICU discharge or death, assessed up to 60 days.

To assess the relationship between low serum magnesium levels and all-cause mortality among critically ill ICU patients.

次要结局

未报告次要终点

研究者

发起方
Bangladesh Bioscience Research Group
申办方类型
Network
责任方
Principal Investigator
主要研究者

Pair Ahmed Jiko

Lab-Incharge (Biochemist)

Bangladesh Medical Research Council (BMRC)

研究点 (1)

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