Perioperative response of arginine vasopressin and aquaporin-2 in cardiac surgery
Not Applicable
- Conditions
- heart disease required cardiac surgery
- Registration Number
- JPRN-UMIN000036594
- Lead Sponsor
- ippon Medical School
- Brief Summary
Median plasma arginine vasopressin levels significantly increased to 1.5,15.3*,2.2,1.7(pg/mL) preoperatively, on postoperative days 1, 4, and 7, respectively (*: p=0.0001). Similarly, levels of urine aquaporin-2 markedly increased in 3.4, 25.8**, 9.3, 5.4(ng/mL), respectively (**p=0.0004).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 8
Inclusion Criteria
Not provided
Exclusion Criteria
emergency cases or critical cases required management in ICU before surgery, hemodialysis cases
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method changes in P-AVP and U-AQP2
- Secondary Outcome Measures
Name Time Method regression of AVP and AQP2, regression of BNP