Mupirocin ointment effect on Polyposis recurrence after Sinus surgery
Phase 2
Completed
- Conditions
- Chronic Rhinosinusitis with Nasal Polyposis.Chronic sinusitis
- Registration Number
- IRCT20221013056165N1
- Lead Sponsor
- Iran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 22
Inclusion Criteria
Patients with CRSwNP candidate for surgery
Lund-Mackay scores and Lund-kennedy scores were almost same at both sides of the nose and sinuses
Exclusion Criteria
Nasal polyposis due to neoplasm, autoimmune diseases, Fungal rhinosinusitis and ect except Chronic Rhinosinusitis with Nasal Polyposis
Patients with Lund-Mackay and Lund-Kennedy scores were significantly different at both sides of the nose and sinuses
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie mupirocin's efficacy in reducing nasal polyposis recurrence post-FESS?
How does mupirocin ointment compare to standard-of-care topical corticosteroids in preventing polyposis recurrence after sinus surgery?
Are there specific biomarkers that correlate with response to mupirocin treatment in CRSwNP patients following FESS?
What are the potential adverse events associated with intranasal mupirocin application in post-surgical CRSwNP management?
What combination therapies involving mupirocin show promise in treating chronic rhinosinusitis with nasal polyposis?