NL-OMON38735已完成不适用
The influence of controlled dehydration and the antidiuretic hormone on blood coagulation - ADH study- part 2
Slotervaartziekenhuis0 个研究点目标入组 12 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 12
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •a. Adults * 18 years old.
- •b. Able to provide informed consent.
- •c. Diagnosis of central diabetes insipidus (DI). (only for patients)
排除标准
- •a. Strong suspection of an infection of any cause (for 6 patients) see definition of infection
- •b. Primary polydipsia and diabetes insipidus.
- •c. Untreated thyroid and adrenal hormone abnormalities.
- •d. Pregnancy or puerperium.
- •e. Common etiologies of the syndrome of inappropriate antidiuretic hormone (SIADH); Active malignancy, inflammatory diseases (multiple sclerosis, meningitis, systemic lupus erythematosus), acquired immuno- deficiency syndrome (AIDS), infections (tuberculosis, pneumonia, empyema) (only for those 6 patients without signs of infection), cystic fibrosis, drugs (Selective serotonine reuptake inhibitors, tricyclic antidepressants, carbamazepine, clofibrate, narcotics, antipsychotic drugs, cytotoxic drugs)
- •f. Potentiation of AVP antidiuretic effects: desmopressin, vasopressin, oxytocin, prostaglandin synthesis inhibitors
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