Study on the effect and mechanism of Supplementing Qi, Nourishing Yin and Dredging Collaterals on diabetic microangiopathy
- Conditions
- Diabetic microangiopathy
- Registration Number
- ITMCTR2000003437
- Lead Sponsor
- Gansu Traditional Chinese Medicine Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- Not specified
(1) T2DM with mild to moderate DR and low to moderate DKD;
(2) TCM dialectics for deficiency of Qi and Yin;
(3) HbA1c <= 9.0%, blood pressure < 140 / 90mmHg;
(4) Aged 18-78 years;
(5) Informed consent, voluntary test.
(1) Patients with severe heart, liver and hematopoiesis disorders and psychosis.
(2) Patients with severe infection, diabetic ketoacidosis and hyperkalemia were found.
(3) Pregnant, pregnant or lactating women.
(4) Those who have participated in other clinical trials in the past 3 months.
(5) It is difficult to evaluate the fundus image with the turbid refractive media.
(6) Patients with glaucoma, uveitis, senile macular degeneration and optic neuropathy.
(7) Patients with acute and chronic glomerulonephritis, primary nephrotic syndrome, urinary tract infection and other urinary diseases.
(8) It is confirmed by examination that kidney disease is caused by primary hypertension and other systemic diseases.
Study & Design
- Study Type
- Interventional study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fundus diseases;ß 2-microglobulin;TCM syndrome;Cystatin-C;vision;Homocysteine;renal function;
- Secondary Outcome Measures
Name Time Method glycosylated hemoglobin;blood pressure;Five items of blood lipid;