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Is the use of bloodplatelets effective in the treatment of difficult fistulas related to the anal sfincter?

Completed
Conditions
platelet rich plasma, peri-anal fistulastrombocytenrijk plasma, peri-anale fistels
Registration Number
NL-OMON20536
Lead Sponsor
Maastrich University Medical Centeradress: P.Debyelaan 25 6229 HX Maastrichtphonenumber: 043-387 65 43
Brief Summary

van der Hagen SJ, baten CG, Soters PB, van Gemert WG. Autologous platelelet derived grow factors(platelet rich plasma) as an adjunct to mucosal advancement flap in high cryptoglandular peri-anal fistulae: a pilot study. Colorectal Dis. 2009 Jul 3.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
Not specified
Target Recruitment
120
Inclusion Criteria

1. Age 18-80 years;

2. Able to understand informed consent;

Exclusion Criteria

1. Pregnancy;

2. Local malignancy;

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Recurrent fistulas. The surgeon or docter in the outpatient clinic will decide if there is a recurrent fistula or not. In case of doubt a MRI will be made.
Secondary Outcome Measures
NameTimeMethod
1. Visual analogue scale (VAS-score);<br /><br>2. Quality of life (SF-36 questionnare);<br /><br>3. Incontinence (Vaizey score).
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