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eg muscle activity patterns during walking in healthy young and old adults

Conditions
veroudering
aging
senescence
Registration Number
NL-OMON48092
Lead Sponsor
Centrum voor Bewegingswetenschappen, Sector F
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Pending
Sex
Not specified
Target Recruitment
32
Inclusion Criteria

The young subjects will be between 20 and 30 years old, whereas the old subjects will be 65+ years old. All the
participants will be generally healthy and able to walk without an assistive aid (i.e. walker, cane).

Exclusion Criteria

Mini Mental State Examination score < 24, cardiovascular disorders that causes risk with exercise, high blood pressure that is uncontrolled by medication (> 180/115), previous stroke, Parkinson's disease, Alzheimer's disease or other forms of dementia, treatment of cancer within the last three months, severe asthma or chronic bronchitis, musculoskeletal disorders that disables a person from normal walking, joint replacement or a fracture present in one of the lower extremities, severe diabetes with neuropathy, visual impairments that disables normal mobility, BMI > 30 kg/m2, pregnancy.

Study & Design

Study Type
Observational non invasive
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>Average muscle activity (in mV) of uniarticular leg extensor muscles (i.e.<br /><br>gluteus maximus, vastus lateralis, vastus medialis, soleus) during positive and<br /><br>negative joint work separately.</p><br>
Secondary Outcome Measures
NameTimeMethod
<p>Average muscle activity (in mV) of biarticular leg muscles (i.e. biceps<br /><br>femoris, semitendinosus, rectus femoris, gastrocnemius medialis) and<br /><br>uniarticular leg flexor muscles (i.e. tibialis anterior) during positive and<br /><br>negative joint work separately.<br /><br><br /><br>Time duration of muscle activity (in ms) of leg flexor and extensor muscles<br /><br>during positive and negative joint work separately.<br /><br><br /><br>Joint kinetics during gait:<br /><br>- Negative joint work (hip, knee, ankle) (in J/kg/m)<br /><br>- Positive joint work (hip, knee, ankle) (in J/kg/m)<br /><br><br /><br>Subject anthropometrics:<br /><br>- Body height<br /><br>- Body weight</p><br>
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