ACTRN12621001233819
Completed
未知
Efficacy and safety of deep brain stimulation to thalamic centromedian nucleus in Lennox-Gastaut syndrome (ESTEL): a randomised, double-blind, placebo-controlled epilepsy treatment trial
Associate Professor John ARCHER0 sites20 target enrollmentSeptember 13, 2021
Overview
- Phase
- 未知
- Intervention
- Not specified
- Conditions
- ennox-Gastaut Syndrome
- Sponsor
- Associate Professor John ARCHER
- Enrollment
- 20
- Status
- Completed
- Last Updated
- 4 years ago
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •i) an electroclinical diagnosis of LGS; ii) generalised paroxysmal fast activity (GPFA) and slow spike\-and\-wave (SSW) on interictal EEG; and iii) generalised tonic seizures documented on prior video\-EEG monitoring or clearly described by a reliable eyewitness
Exclusion Criteria
- •i) participants with elevated risks for bleeding; ii) cerebral anatomical variations precluding safe CM\-DBS implantation; iii) predominant seizure type being focal impaired awareness seizures; iv) current or prior psychogenic non\-epileptic seizures
Outcomes
Primary Outcomes
Not specified
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