Imaging Protocol Design for Anti-Angiogenesis Tracking With MRI
试验速览
- 阶段
- 1 期
- 状态
- 终止
- 入组人数
- 12
- 试验地点
- 2
- 主要终点
- To provide preliminary data for a larger study that this type of imaging can be used to monitor the effectiveness of anti-angiogenic therapy.
研究概览
简要总结
Preliminary imaging study to test for future use of this MRI-imaging for evaluating anti-angiogenesis treatment.
详细描述
The purpose of this study is to develop and evaluate new MR imaging techniques and protocols for non-invasive monitoring of anti-angiogenesis treatment of breast cancer. This feasibility study is a preliminary imaging study to test this imaging protocol on subjects already undergoing MR for clinical purposes.
The specific objective of this research study is to develop and validate both MRI and functional MRI data acquisition methods, task paradigms, and post-processing techniques to ensure reliability of results.
The information derived from this research is intended to be applied to a future study of subjects undergoing experimental anti-angiogenesis drug therapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Age 18 years or greater
- •Undergoing breast MRI exam
排除标准
- •Pregnancy
- •Contraindication for MRI on standard screening checklist for clinically indicated examinations (i.e. metal devices/implants; history of claustrophobia)
- •History/presence of any of the following to the breast: injury; breast implant; surgical or interventional procedure; clinically significant abnormality
结局指标
主要结局
To provide preliminary data for a larger study that this type of imaging can be used to monitor the effectiveness of anti-angiogenic therapy.
时间窗: After analysis of images
次要结局
未报告次要终点