跳至主要内容
临床试验/CTRI/2024/05/068062
CTRI/2024/05/068062尚未招募4 期

Prospective Non Randomized interventional study to compare the effect of spinal anaesthesia versus general anaesthesia on Blood Glucose concenteration in patients undergoing lower abdominal surgeries at SMS Medical College and Hospital,Jaipur

Department of Anaesthesiology2 个研究点 分布在 1 个国家目标入组 70 人开始时间: 2024年6月15日最近更新:

试验速览

阶段
4 期
状态
尚未招募
发起方
入组人数
70
试验地点
2
主要终点
Mean Blood Glucose Concenteration

研究概览

简要总结

The Etiology of hyperglycemia is multifactorial , but is thought primarily to be the result of activation of the sympathoadrenal system ,with contributions from the hypothalamus and adenohypophysis. The stress response triggers an increase in levels of plasma catecholamines and glucocorticoids ,which in turn lead to hyperglycemia . cortisol also has a huge impact on the glucose metabolism in stress, because by increasing glycogenolysis and glucogenesis it can lead to hyperglycemia . the aim of the study is t determine the significance of spinal anaesthesia in supressing the metabolic , and hemodynamic response to surgical stress during and after elective abdominal urological and orthopaedics surgery compared with the technique of general anaesthesia

研究设计

研究类型
Interventional
分配方式
Not Applicable
盲法
Not Applicable

入排标准

年龄范围
18.00 Year(s) 至 60.00 Year(s)(—)
性别
All

入选标准

  • •1.Patients undergoing scheduled elective surgeries 2.patients willing to give informed written consent 3.ASA Grade 1 and 2.

排除标准

  • •1.Any Cardiovascular disorder 2.Any Respiratory Disorder 3.diabetic patients 4.Hypertensive patients 5.Neurological disorders 6.Drug allergy , if any.

结局指标

主要结局

Mean Blood Glucose Concenteration

时间窗: 5 minutes before induction | 5 minutes after induction | 5 minutes before completion | 30 minutes after completion

次要结局

  • Mean Hemodynamic variables(Baseline)

研究者

发起方
Department of Anaesthesiology
申办方类型
Government medical college

研究点 (2)

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