SURF studie
Recruiting
- Conditions
- Healthy volunteersCharacteristics of oxycodone and tapentadol.
- Registration Number
- NL-OMON23681
- Lead Sponsor
- eiden University Medical Center
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 24
Inclusion Criteria
Healthy according to medical history, physical examination, vital signs, lab values, and ECG;
- Age 18-38 years;
Exclusion Criteria
- Presence of health issues including presence or history of any psychiatric, medical or neurologic disorder that may interfere with the current study (eg. neuropathic pain conditions);
- Presence or a history of illicit drug use or excessive alcohol consumption (>21 units per week),
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method - Changes in breath-to-breath minute ventilation as measured at iso-hypercapnia; <br /><br>- Change in nociception using experimental pain models<br>
- Secondary Outcome Measures
Name Time Method The drug concentration, respiratory and pain end-points will be used for construction of the Utility Functions.