A study to check the effect an interaction of two anaesthestic drugs have on the human body.
Not Applicable
- Conditions
- Health Condition 1: O- Medical and Surgical
- Registration Number
- CTRI/2020/06/026101
- Lead Sponsor
- PGIMER Chandigarh
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Seventy five ASA physical status I and II patients of either gender aged 18- 65 y scheduled to undergo surgery under general anesthesia
Exclusion Criteria
a)ASA grade III and above.
b)History of hypersensitivity to drugs used in study.
c)Patients suffering from psychiatric illnesses on medications.
d)Intake of barbiturates or any other enzyme inducing drugs in the last 3 months.
e)Patient on any kind of pain medications.
f)Morbidly obese patients.
g)Patients who are chronic smokers or those that smoke more than 1 pack of cigarettes daily.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To study the effect of fentanyl on propofol dose requirement using target controlled infusion in Indian patients.Timepoint: Only at time of study. I.e 0 month.
- Secondary Outcome Measures
Name Time Method To assess the target plasma concentration of propofol required to achieve unconsciousness (loss of verbal response- MOAA/S scale 3) and anesthesia (loss of sensory stimulus response- MOAA/S scale 0) with fentanyl TCI at 1ng/ml, 1.5ng/ml, 2ng /ml.Timepoint: Only at time of study. I.e 0 month.