MedPath

IMproving FItness in NEuromuscular diseases

Recruiting
Conditions
NMD
Neuromuscular diseases
10029317
Registration Number
NL-OMON50618
Lead Sponsor
Academisch Medisch Centrum
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Recruiting
Sex
Not specified
Target Recruitment
90
Inclusion Criteria

(1) Prior paralytic poliomyelitis (confirmed by signs of residual weakness and
atrophy of muscles on neuromuscular examination, and with EMG) or diagnosis of
PPS (according to the March of Dimes criteria), CMT (confirmed by DNA testing
or polyneuropathy compatible with CMT and positive family history), or other
slowly progressive NMD (with no effective drug therapy).
(2) Presence of a question for help indicative of impaired physical fitness or
physical inactivity.
(3) Minimum age of 18 years.

Exclusion Criteria

(1) Contraindication for being physically active (according to the guidelines
by the American College of Sports Medicine).
(2) Unable to follow verbal or written instructions.
(3) Insufficient mastery of the Dutch language.
(4) Engaged in an exercise program for a period longer than 4 weeks during the
last 6 months.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
<p>(1) Physical fitness<br /><br>The primary endpoint will be the change in peak oxygen uptake directly after<br /><br>intervention.</p><br>
Secondary Outcome Measures
NameTimeMethod
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