Prevention of Depressive Relapse by Means of Physical Exercise and Lifestyle
- Conditions
- Depression
- Registration Number
- NCT02599597
- Lead Sponsor
- Lund University
- Brief Summary
Depression treatments including physical activity and sleep management has been shown to relieve depressive symptoms among participants suffering depressive episodes. This study evaluates the potential of these methods as prevention of depressive relapse or recurrence
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 150
- A history of at least one episode of Major Depression.
- If medicating - Taking a stable (since one month) and therapeutic dosage of antidepressant medication
- Being able to read and write Swedish
- Having access to the internet
- Fulfilling the criteria for Major depression
- Bipolar disorder
- Psychosis
- Substance abuse
- Suicidality
- Currently in psychotherapy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Depressive relapse (change in diagnostic status, SCID-I) Baseline - 12 months Monthly screening via Montgomery-Asberg Depression Rating Scale - Self rated \& Structured Clinical Interview for DSM IV
Change from baseline in depressive symptoms (MADRS-S) Monthly, 0-12 months Change in depressive symptoms will be measured by an internetbased version of the Montgomery-Asberg Depression Rating Scale - Self rated.
- Secondary Outcome Measures
Name Time Method Change from baseline in the International Physical Activity Questionnaire (IPAQ) Baseline - 12 months The International Physical Activity Questionnaire is a measure of physical activity
Morisky Medication Adherence Scale (MMAS-8) Baseline - 12 months Self-reported measure of medication adherence
Time to depressive relapse Baseline - 12 months Time to depressive relapse is recorded as secondary outcome variable
Self reported treatment seeking Baseline - 12 months Treatment seeking among participants is recorded as secondary outcome variable
Change from baseline in Outcomes Questionnaire 45 (OQ-45) Baseline - 12 months The OQ-45 measures functioning in 3 domains: Symptom distress (heavily loaded for depression and anxiety), Interpersonal functioning, and Social Role. It enables the clinician to assess functional level and change over time.
Change from baseline in health related quality of life (EQ-5D) Baseline - 12 months Health related quality of life will be measured by an internet based version of the EQ-5D.
Insomnia Severity Index (ISI) Baseline - 12 months Insomnia issues
Alcohol Use Disorder Identification Test (AUDIT) Baseline - 12 months
Trial Locations
- Locations (1)
Vuxenpsykiatrimottagning allmänpsykiatri Fosievägen Malmö
🇸🇪Malmö, Skåne, Sweden
Vuxenpsykiatrimottagning allmänpsykiatri Fosievägen Malmö🇸🇪Malmö, Skåne, Sweden