Prevention of Depressive Relapse by Means of Physical Exercise and Lifestyle

Lund University1 site in 1 country150 target enrollmentFebruary 2016

ConditionsDepression

Overview

Phase: Not Applicable
Intervention: Not specified
Conditions: Depression
Sponsor: Lund University
Enrollment: 150
Locations: 1
Primary Endpoint: Depressive relapse (change in diagnostic status, SCID-I)
Status: Completed
Last Updated: 6 years ago

Overview Investigators Eligibility Criteria Outcomes Sites Similar Trials

Overview

Brief Summary

Depression treatments including physical activity and sleep management has been shown to relieve depressive symptoms among participants suffering depressive episodes. This study evaluates the potential of these methods as prevention of depressive relapse or recurrence

Registry

clinicaltrials.gov

Start Date

February 2016

End Date

December 1, 2019

Last Updated

6 years ago

Study Type

Interventional

Study Design

Parallel

Sex

All

Investigators

Sponsor

Lund University

Responsible Party

Principal Investigator

Olof Johansson

PhD student

Lund University

Eligibility Criteria

Inclusion Criteria

•A history of at least one episode of Major Depression.
•If medicating - Taking a stable (since one month) and therapeutic dosage of antidepressant medication
•Being able to read and write Swedish
•Having access to the internet

Exclusion Criteria

•Fulfilling the criteria for Major depression
•Bipolar disorder
•Psychosis
•Substance abuse
•Suicidality
•Currently in psychotherapy

Outcomes

Primary Outcomes

Depressive relapse (change in diagnostic status, SCID-I)

Time Frame: Baseline - 12 months

Monthly screening via Montgomery-Asberg Depression Rating Scale - Self rated \& Structured Clinical Interview for DSM IV

Change from baseline in depressive symptoms (MADRS-S)

Time Frame: Monthly, 0-12 months

Change in depressive symptoms will be measured by an internetbased version of the Montgomery-Asberg Depression Rating Scale - Self rated.

Secondary Outcomes

Change from baseline in the International Physical Activity Questionnaire (IPAQ)(Baseline - 12 months)
Morisky Medication Adherence Scale (MMAS-8)(Baseline - 12 months)
Time to depressive relapse(Baseline - 12 months)
Self reported treatment seeking(Baseline - 12 months)
Change from baseline in Outcomes Questionnaire 45 (OQ-45)(Baseline - 12 months)
Change from baseline in health related quality of life (EQ-5D)(Baseline - 12 months)
Insomnia Severity Index (ISI)(Baseline - 12 months)
Alcohol Use Disorder Identification Test (AUDIT)(Baseline - 12 months)