Prospective cohort study of chronic diarrhea treatment

Not Applicable

Recruiting

• Conditions: chronic diarrhea

• Registration Number: JPRN-UMIN000051774
• Lead Sponsor: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2023-08-01
• Last Update Posted: 17 October 2023
• Study Completion: 2030-12-31

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 800

Inclusion Criteria

Not provided

Exclusion Criteria

Patients with organic disease as a possible cause of diarrheal symptoms. Other patients who are deemed inappropriate for inclusion in the study by the investigators.

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Percentage reduction in daily stool frequency with diarrhea medications

Secondary Outcome Measures

Name	Time	Method
Correlation of disease background and symptoms with efficacy of diarrhea medications (lower gastrointestinal endoscopy findings, abdominal X-ray findings, abdominal CT findings, enterography findings, blood test findings, rectal manometry findings, colon function test findings, blood pressure, abdominal and mental symptoms at presentation (GI symptoms questionnaire, HADS questionnaire, WPAI:GH questionnaire, Bristol stool Scale)). Association of symptoms with quality of life, labor productivity, anxiety and depression in diarrhea. Safety of diarrhea medications.