Effects of Pursed Lip Breathing on Muscle Oxygenation During walking with a portable oxygen concentrator in Interstitial Lung Disease
Not Applicable
Completed
- Conditions
- Diseases of the respiratory system
- Registration Number
- KCT0005440
- Lead Sponsor
- Pusan National University Hospital
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
Interstitial Lung disease patients who diagnosed by forced vital capacity (FVC) <80 % or diffusion capacity (DLCO)<80 %, Adult men and women over 20 years old
Exclusion Criteria
1. Subjects with severe hypoxia (less than 88% of SpO2) at rest
2. Subjects who are limited in 6-minute gait test due to musculoskeletal problems of legs or feet
3. Subjects with limited activity due to heart disease (heart failure NYHA II~IV)
4. Subjects with pain while walking due to arteriovenous vascular disease
5. Subjects who do not understand the test due to cognitive decline
6. Subjects with obesity whose fat thickness of the quadriceps muscle exceeds 1cm
7. Subjects with muscle disease (myositis, myopathy)
8. Pregnant women
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method SmO2% change during exercise (SmO2rest-SmO2nadir)
- Secondary Outcome Measures
Name Time Method 6-minute walk distance (6MWD);NIRS (deoxy-hemoglobin, deoxy-myoglobin(HHb rest), HHb(peak), oxy-hemoglobin, oxy-myoglobin (HbO2, rest), HbO2(peak), total hemoglobin, myoglobin (THb = HHb+HbO2), Hb difference (Hbdiff = HbO2-HHb);Pulmonary function test (FEV1, FVC, FEV1/FVC);SpO2% change during exercise (SmO2rest-SmO2nadir)