Etomidate-based sedation in ERCP
Not Applicable
Completed
- Conditions
- Not Applicable
- Registration Number
- KCT0001926
- Lead Sponsor
- Hallym University Medical Center-Dongtan
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 128
Inclusion Criteria
Age: 20–80 years
Needs for endoscopic retrograde cholangiopancreatography
American Society of Anesthesiologists (ASA) physical status I–II
Exclusion Criteria
1. a history of adverse events with prior sedation
2. known hypersensitivity to egg products, soy beans, etomidate, propofol, or its emulsifier
3. known adrenocortical insufficiency, chronic corticoid therapy, or porphyria
4. severe renal failure (serum creatinine level >2 mg/dl)
5. pregnant or breast-feeding
6. desire to have endoscopy without sedation
7. unable to provide informed consent
8. baseline mean blood pressure (MBP) <60 mmHg
9. baseline oxygen saturation (SpO2) <90% in room air or <95% with 2 L/min oxygen
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method overall respiratory event
- Secondary Outcome Measures
Name Time Method overall cardiovascular event;administered dose of sedatives;change of vital signs (SpO2, MBP, and HR)