Calcitriol combined with ergocalciferol in CKD with proteinuria
Not Applicable
- Conditions
- Do both natural vitamin D (ergocalciferol) and active viatamin(calcitriol) decrease proteinuria in CKD stage 3 and 4 with proteinuria more than 1 gram/day?
- Registration Number
- TCTR20140929002
- Lead Sponsor
- Faculty of Medicine,Chulalongkorn University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 140
Inclusion Criteria
the patients are age more than 18 years old and
1. Chronic kidney failure stage 3 -4
2.proteinuria mora than 1 gram per day
3. Serum 25(OH)D (vitamin D level) less than 30 ng/ml
Exclusion Criteria
1.active glomerulonephritis
2.recieve immunosuppressive drug within 3 months
3.adjust dose of ACEI/ARB , Phosphate binder or recieve within 3 months before enrollment
4.serum Calcium more than 10.2 mg/dl
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method proteinuria 12 wk urine protein creatinine ratio
- Secondary Outcome Measures
Name Time Method progression of kidney function 12 wk serum creatinine