Dexmedetomidine Versus Pentobarbital for Pediatric Procedural Sedation
Not Applicable
Withdrawn
- Conditions
- Sedation
- Interventions
- Registration Number
- NCT00878345
- Lead Sponsor
- Washington University School of Medicine
- Brief Summary
The investigators believe dexmedetomidine will provide superior sedation with reduced side effects and reduced time to discharge compared with pentobarbital. The investigators have developed sedation protocols with pentobarbital and dexmedetomidine in our ambulatory procedure center. These protocols are both routinely used for sedation in our unit. The investigators propose to study these two protocols in children ages 6 months to 6 years presenting to the ambulatory procedure center for non-painful procedural sedation. The investigators will compare failure of sedation, side effect profile, recovery and discharge times between the two pharmacologic protocols.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- WITHDRAWN
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
- Requiring sedation for non-painful procedures
- Normal airway per exam
Exclusion Criteria
- Congenital syndromes with known difficult airways
- Known difficult airway during past anesthesia or sedation experience
- Parent/guardian refusal of participation
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description 2 pentobarbital sedation protocol Pentobarbital sedation protocol 1 dexmedetomidine sedation protocol Dexmedetomidine sedation protocol
- Primary Outcome Measures
Name Time Method failure of sedation day of sedation
- Secondary Outcome Measures
Name Time Method side effect profile 48 hours post-sedation recovery and discharge time day of sedation
Trial Locations
- Locations (1)
St. Louis Children's Hospital
🇺🇸Saint Louis, Missouri, United States