Dexmedetomidine Versus Pentobarbital Sedation Protocol for Non-painful Procedural Sedation in Pediatrics
Overview
- Phase
- Not Applicable
- Intervention
- dexmedetomidine sedation protocol
- Conditions
- Sedation
- Sponsor
- Washington University School of Medicine
- Locations
- 1
- Primary Endpoint
- failure of sedation
- Status
- Withdrawn
- Last Updated
- 7 years ago
Overview
Brief Summary
The investigators believe dexmedetomidine will provide superior sedation with reduced side effects and reduced time to discharge compared with pentobarbital. The investigators have developed sedation protocols with pentobarbital and dexmedetomidine in our ambulatory procedure center. These protocols are both routinely used for sedation in our unit. The investigators propose to study these two protocols in children ages 6 months to 6 years presenting to the ambulatory procedure center for non-painful procedural sedation. The investigators will compare failure of sedation, side effect profile, recovery and discharge times between the two pharmacologic protocols.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Requiring sedation for non-painful procedures
- •Normal airway per exam
Exclusion Criteria
- •Congenital syndromes with known difficult airways
- •Known difficult airway during past anesthesia or sedation experience
- •Parent/guardian refusal of participation
Arms & Interventions
1
Dexmedetomidine sedation protocol
Intervention: dexmedetomidine sedation protocol
2
Pentobarbital sedation protocol
Intervention: pentobarbital sedation protocol
Outcomes
Primary Outcomes
failure of sedation
Time Frame: day of sedation
Secondary Outcomes
- side effect profile(48 hours)
- post-sedation recovery and discharge time(day of sedation)