ACTRN12618000386235尚未招募未知
Establishing an Australian reference range for striatal binding in patients with Parkinson’s disease and healthy controls with 6-[18F]fluoro-L-3,4-dihydroxyphenylalanine (F-DOPA) PET.
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 Years 至 o limit(—)
- 性别
- All
入选标准
- •Parkinson's disease: based on the UK Brain bank clinical criteria and a Hoehn and
- •Yahr score of 2.5 or less (early PD) or 3.0 or more (late PD).
- •Normal controls: aged matched individuals with no historical or clinical evidence of
- •any neurological disorder.
- •Greater than 18 years of age
- •Able to undertake PET imaging
- •Able to provide written informed consent
排除标准
- •Less than 18 years of age
- •Medical contraindication to PET or MRI imaging
- •Patients with concurrent psychiatric disorders, signs of severe cognitive deterioration and severe cardiovascular comorbidity.
- •Cognitive impairment considered to impair the ability to give written informed consent in the opinion of the treating clinician
研究者
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