Laser Therapy on Orthodontic Tooth Movement
Not Applicable
Completed
- Conditions
- Laser TherapyOrthodontic Tooth MovementBone Remodeling
- Registration Number
- NCT04070170
- Lead Sponsor
- Ildeu Andrade Jr.
- Brief Summary
The aims of this study will be to evaluate if a Lower Level Laser Therapy (LLLT): (1) enhances the levels of important pro-inflammatory chemokines involved in the bone remodeling process; (2) increases the rate of orthodontic tooth movement (OTM) on human subjects.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 24
Inclusion Criteria
- Facial convexity
- Protrusion or biprotrusion of the incisors
- Dental crowding
- Healthy periodontal condition
- Satisfactory oral hygiene
Exclusion Criteria
- Patients under medications that may interfere with bone metabolism, such as anti-inflammatory, antibiotics and hormonal supplements in the previous three months
- Skeletal crossbite
- Parafunctional habits
- Occlusal interference
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method Rate of orthodontic tooth movement, with and without low-level laser therapy The quantification of OTM was performed after 3 months of canine retraction The canine retraction was measured with a digital dynamometer
- Secondary Outcome Measures
Name Time Method Chemokine levels in the periodontal tissue after LLLT and orthodontic force The chemokine levels were assayed on days 0, 1, 7 and 14 after application of orthodontic force and low-level laser therapy The chemokine levels were measured in the periodontal tissue after LLLT and orthodontic force by means of a cytometric bead array (CBA)
Trial Locations
- Locations (1)
Pontifical Catholic University of Minas Gerais
🇧🇷Belo Horizonte, MG, Brazil
Pontifical Catholic University of Minas Gerais🇧🇷Belo Horizonte, MG, Brazil