Exertional dyspnea in patients with suspected heart failure with preserved ejection fraction: are symptoms really caused by impaired left ventricular filling? * A prospective case-control study - Exertional dyspnea in HFPEF

Medisch Universitair Ziekenhuis Maastricht0 个研究点目标入组 36 人开始时间: 待定最近更新: 2024年5月6日

适应症

试验速览

暂无简介。

•Group 1: Patients with exertional dyspnea thought to be caused by HFPEF
•- Exertional dyspnea (NYHA functional class 2 or higher)
•- All common causes of exertional dyspnea are excluded such as pulmonary disease, anaemia, myocardial ischemia, pulmonary hypertension, systolic heart failure, severe valvular disease, according to the diagnostic algorithm in figure 2.
•Group 2: Patients suffering from hypertension
•- Patient suffering from pulmonary hypertension, scheduled for right-sided heart catheterisation

•-Inability to give informed consent or refusal to participate in the study
•-Acute or chronic physical impairment (other than dyspnea) limiting the ability to comply with study requirements
•-Age <18 years
•-Body mass index (BMI) of > 32 kg/m2
•-Use of oral anticoagulation
•-History of stress-induced syncope or ventricular tachycardia during exercise
•-Significantly impaired left ventricular ejection fraction, i.e. LVEF < 45%
•-Symptoms and signs of congestive heart failure at rest (i.e. NYHA IV)
•-Angina pectoris CCS > 2 or signs of silent ischemia during stress-testing (ergospirometry)
•-Impaired pulmonary function assessed by spirometry

发起方

Medisch Universitair Ziekenhuis Maastricht