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临床试验/NCT06551168
NCT06551168招募中不适用

The Cardiovascular, Hematological, and Performance Response to Heat Acclimation in Healthy Trained Females

Trinity Western University2 个研究点 分布在 1 个国家目标入组 14 人开始时间: 2024年9月1日最近更新:
适应症

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
14
试验地点
2
主要终点
Performance

研究概览

简要总结

Heat acclimation is when you repeatedly exposure yourself to heat so that your body adapts and better tolerates heat.

This project will determine if completing a heat acclimation maintenance period after heat acclimation is more beneficial than heat acclimating alone for exercise performance in the heat. To determine this, participants will exercise in the heat before heat acclimation, after heat acclimation, and after heat acclimation maintenance. Researchers will assess the heart's pumping capacity, blood volume, body temperature, and exercise performance to determine which approach is more effective.

详细描述

Purpose and Hypothesis: Global warming combined with increased frequency of heat waves exposes those who are working, exercising, or competing outdoors to considerable thermal strain. Excessive heat stress decreases exercise performance and can lead to heat illnesses. Deliberate serial exposure to natural (acclimatization) or artificial (acclimation) heat (HA) is the most efficacious method to defend homeostasis at rest and during exercise in hot environments. Our project will determine if three weeks of heat acclimation maintenance (HAM) further potentiates exercise performance in the heat than exercise performance measured after 10 days of HA in females.

Justification: Female participation in arduous occupations and professional sport is increasing. Presently a paucity of data regarding the female response to heat acclimation exist. Findings from this study will help females undertake effective and efficient strategies to mitigate thermal strain.

Research design: This is an experimental trial with a treatment and a control group. VO2max, plasma volume (PV), core temperature, and cardiac output will be measured pre-, mid-, and post-intervention. Participants will complete 10 sessions of HA over two weeks. Participants will then undergo three weeks of HAM with three heat sessions per week. A heat performance test will be completed pre-, mid-, and post-intervention to examine performance changes. A control group will complete the same test schedule but will not perform any HA or HAM.

Statistical analysis

Sample size will be 8 females in the experimental and 6 females in the control group. Data will be analyzed for normality using the Shapiro-Wilk test. Descriptive statistics will be presented as the mean and standard deviation. Statistical significance will be determined at P <0.05. A two-way repeated measure ANOVA will be used to measure differences between groups and hemodynamic, cardiovascular and performance variable differences pre- and post-HA, and pre- post-HAM. If significant effects are present, these will be followed by a post-hoc Tukey's test. Pearson's r correlations (two-tailed) will be conducted between VO2max, and intravascular volumes and heat performance test outcome.

研究设计

研究类型
Interventional
分配方式
Non Randomized
干预模型
Parallel
主要目的
Basic Science
盲法
None

入排标准

年龄范围
18 Years 至 55 Years(Adult)
性别
Female
接受健康志愿者

入选标准

  • Familiar with the sport of cycling and own a bicycle and smart trainer (or a trainer and a power meter).
  • Endurance athlete or currently engaging in endurance exercise
  • Maximal oxygen consumption (VO2max) greater than 40 ml/kg/min
  • Between the ages of 18 and 55
  • Able to speak, read, and write in English

排除标准

  • Unable to exercise
  • Previous or current heat intolerance

结局指标

主要结局

Performance

时间窗: 2 weeks and 5 weeks

Participants will complete a timetrial on a cycle ergometer in a heat chamber. Faster times following HA or HAM will be considered a marker of performance

次要结局

  • Intravascular volumes(2 weeks and 5 weeks)

研究者

发起方
Trinity Western University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Anita Cote

Associate Professor

Trinity Western University

研究点 (2)

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