The Influence of Lidocaine Volume on Discomfort During Administration of Local Anesthetic

Not Applicable

Completed

• Conditions: Needlestick Injuries
• Interventions: Procedure: 2 ml 1% Lidocaine; Procedure: 1 ml 2% Lidocaine

• Registration Number: NCT02086292
• Lead Sponsor: Norwegian University of Science and Technology

Brief Summary

The aim of the study is to find a simple method for pain reduction that can be used in clinical practice when administering digital nerve block with a single subcutaneous injection. It will be investigated whether a smaller volume of lidocaine can decrease pain during injection.

Detailed Description

Healthy volunteers will receive a single subcutaneous injection digital nerve block at the base of each ring finger. 2ml 1% lidocaine in one of the fingers, and 1 ml 2% lidocaine in the other. After each injection, the subject will be asked to evaluate the pain on a visual analog scale (0-100 mm). Additionally the sensibility will be tested with a Semmes-Weinstein monofilament, to evaluate if the different methods achieve desired anesthetic effect.

Study Timeline

• Study Start: 2014-02
• Study First Submitted: 2014-03-11
• Study First Submitted QC: 2014-03-11
• Study First Posted: 2014-03-13
• Primary Completion: 2014-06
• Study Completion: 2014-06
• Status Verified: 2016-09
• Last Update Submitted: 2016-09-15
• Last Update Posted: 2016-09-16

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 36

Inclusion Criteria

• age 18 - 65

Exclusion Criteria

• regular use of analgesics
• known hypersensitivity of local anaesthetic
• renal-, heart- or liver disease
• known peripheral neuropathy or diabetes mellitus
• local infection on injection site
• circulation disorders in upper extremities (e.g. Raynaud´s phenomenon)

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: CROSSOVER

Arm && Interventions

Group	Intervention	Description
2 milliliter lidocaine	2 ml 1% Lidocaine	2 ml 1% Lidocaine in one ring finger, 1 ml 2% Lidocaine in the other ring finger
1 milliliter lidocaine	1 ml 2% Lidocaine	1 ml 1% Lidocaine in one ring finger, 2 ml 2% Lidocaine in the other ring finger

Primary Outcome Measures

Name	Time	Method
pain	60 seconds	1. visual analog scale 0-100mm; 2. questionnaire

Trial Locations

Locations (1)

Department of neuroscience, NTNU; 🇳🇴 Trondheim, Norway