Will Adjusting the pH of Lidocaine Reduce the Pain During Injection of Local Anaesthetic?
Not Applicable
Completed
- Conditions
- Needlestick Injuries
- Interventions
- Procedure: Lidocaine injection with bicarbonateProcedure: lidocaine injection
- Registration Number
- NCT02107716
- Lead Sponsor
- Norwegian University of Science and Technology
- Brief Summary
This study will investigate the influence of adjusting the pH of lidocaine on pain during subcutaneous injection. Each participant will receive two injections on the abdomen with different pH. After each injection, the subject will be asked to evaluate the pain on a Visual analog scale (0-100 mm). It is anticipated that the pain decreases with increasing pH. The aim of the study is to find a simple method for pain reduction that can be used in clinical practice.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 32
Inclusion Criteria
fyll inn
- Age 18-65 years
Exclusion Criteria
- Kidney, heart or liver disease
- Eczema or psoriasis on injection site
- Neuropathy
- Regular use of painkillers
- Hypersensitivity of Lidocaine
- Pregnancy
- Diabetes
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Bicarbonate Lidocaine injection with bicarbonate Each participant will receive two lidocaine injections on the abdomen with different pH Bicarbonate lidocaine injection Each participant will receive two lidocaine injections on the abdomen with different pH
- Primary Outcome Measures
Name Time Method Pain 60 seconds 1. Visual Analog Scale 0-100 mm
2. Questionnaire
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Department of Neuroscience, NTNU
🇳🇴Trondheim, Norway