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Clinical Trials/ISRCTN21521538
ISRCTN21521538
Completed
Not Applicable

A randomised controlled trial of the combined use of paracetamol and ibuprofen to treat febrile childre

Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)0 sites120 target enrollmentSeptember 30, 2005
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ConditionsFeverSigns and Symptoms

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Fever
Sponsor
Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)
Enrollment
120
Status
Completed
Last Updated
11 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSimilar Trials

Overview

Brief Summary

No summary available.

Registry
who.int
Start Date
September 30, 2005
End Date
TBD
Last Updated
11 years ago
Study Type
Interventional
Sex
All

Investigators

Sponsor
Record Provided by the NHSTCT Register - 2005 Update - Department of Health (UK)

Eligibility Criteria

Inclusion Criteria

  • •Children presenting in the BRI children's emergency department with fever.
  • •1\. Age 6 months \- 16 years
  • •2\. Children with a temperature of 38\.0 degrees C or more will be eligible

Exclusion Criteria

  • •1\. Those admitted directly to resuscitation by ambulance or those transferred there following initial clinical assessment
  • •2\. Those eligible for recruitment in any other study running concurrently or those who have been recruited to a simultaneous study of children's fever
  • •3\. Prior administration that will interfere with randomisation: paracetamol within the last six hours or ibuprofen within the last six hours
  • •4\. Allergy to either study drug
  • •5\. Likely dehydration, cellulitis or skin infection, concomitant warfarin or heparin, chronic illness likely to interfere with drug metabolism (kidney or liver disease), immunosuppression, HIV\+, concomitant chemo or radiotherapy, organ or bone marrow transplant recipient, immunosuppressive therapy in the last three months

Outcomes

Primary Outcomes

Not specified

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