Randomized controlled study for concomitant use of 5-aminosalicylic acid suppository with increased dose of oral 5-aminosalicylic acid for moderate to severe patients with ulcerative colitis
Not Applicable
- Conditions
- ulcerative colitis
- Registration Number
- JPRN-UMIN000019310
- Lead Sponsor
- Department of Gastroenterology and Hepatology, Osaka University Graduate School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 90
Inclusion Criteria
Not provided
Exclusion Criteria
Coexisting infectious colitis History of administrating more than 3.0 g of oral 5-ASA, topical 5-ASA, oral corticosteroid, tacrolimus before 30 days of enrollment History of receiving anti-TNF therapy before 60 days of enrollment Regularly administrating NSAIDs before 7 days of enrollment History of administrating topical corticosteroid before 7 days of enrollment Severe renal/liver dysfunction History of allergy for 5-ASA Concomitant malignant disease With pregnancy or lactation Judged as inadequate for this study by the researchers
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The change in partial Mayo score after 4 weeks of therapy
- Secondary Outcome Measures
Name Time Method