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Apneic Oxygenation for Morbid Obese Parturient in cs

Not Applicable
Completed
Conditions
Morbid Obesity
Registration Number
NCT05021549
Lead Sponsor
Ain Shams University
Brief Summary

The aim of this study is to compare the effect of apneic preoxygenation to conventional preoxygenation on the oxygen desaturation in morbid obese parturient performing elective caesarean section under general anesthesia.

Detailed Description

Anesthetic management of the obese parturient is challenging. Both pregnancy and obesity are risk factors for a difficult airway and anesthesia-related maternal mortality. There is increased risk of difficult intubation associated with an increased difficultly in mask ventilation and increased risk of accelerated desaturation during apnea.

The use of apneic oxygenation for the optimization of peri-intubation conditions is a promising means of preventing hypoxemia.

Despite the recommendation of the use of nasal prongs to insufflate oxygen at flows of 5 L/min to 15 L/min during the apneic period randomized controlled trial is still not available in the morbidly obese parturient.

Recruitment & Eligibility

Status
COMPLETED
Sex
Female
Target Recruitment
60
Inclusion Criteria
  1. Morbid obesity parturient defined as a body mass index (BMI) above 40 kg/m2.
  2. ASA physical status I-II
  3. Age above 18 years.
  4. Scheduled for elective caesarean section under general anesthesia.
Exclusion Criteria
  1. Parturient of ASA physical status III or above.
  2. Suspected or known difficult airway (Mallampati class > 2, reduced neck movement, reduced mouth opening, or Cormack-Lehane grade 4 recorded during a previous intubation procedure).
  3. Any contraindication for nasal prong use, for example, tumours, fractures or trauma.
  4. SpO2 ≤ 97% prior to preoxygenation.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
the lowest oxygen saturation recordedduring intubation procedure

percentage

Secondary Outcome Measures
NameTimeMethod
rates of desaturation below SpO2 90%during intubation procedure

percentage

rates of critical desaturation below SpO2 80%during intubation procedure

percentage

Trial Locations

Locations (2)

Ain Shams university

🇪🇬

Cairo, Egypt

Faculty of medicine

🇪🇬

Cairo, Egypt

Ain Shams university
🇪🇬Cairo, Egypt

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