Comparing the efficacy of mouthwash enriched with pomegranate extract versus chlorhexidine mouthwash in the control of plaque and gingivits
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Gingival health will be assessed using Loe and Silness gingival index and plaque scores which will be assessed using Turesky-Gilmore modification of Quingley hein plaque index
研究概览
简要总结
This study is a randomized double blinded clinical trial to compare the efficacy of a pomegranate peel extract mouthwash with chlorhexidine in managing plaque and gingivitis among 20 patients aged between 18 to 40 years with mild to moderate gingivitis. Participants will be assigned to either the pomegranate group or the chlorhexidine group and will be instructed to rinse twice daily for 21 days. Clinical parameters including Plaque Index and Gingival Index will be assessed at baseline 14 days and 21 days. Findings from this study will help determine whether pomegranate which is a natural agent with antimicrobial and anti-inflammatory properties can serve as a safe and effective alternative to chlorhexidine which despite its efficacy is associated with side effects such as tooth staining and altered taste.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 18.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •Systematically healthy voluntary participants Participants with mild to moderate gingivitis With atleast 20 natural teeth present in the mouth Participants who are willing to comply with appointment schedule.
排除标准
- •Participants with any systematic disease Undergoing orthodontic treatment Pregnant and nursing females With positive history of antibiotic, corticosteroid or periodontal therapy in past one month Using antimicrobial mouthwashes Smokers Who refuse to participate in the study.
结局指标
主要结局
Gingival health will be assessed using Loe and Silness gingival index and plaque scores which will be assessed using Turesky-Gilmore modification of Quingley hein plaque index
时间窗: Data will be recorded at the baseline, 14 days and 21 days
次要结局
- Any adverse or unintended effects of mouthwash will be taken as secondary outcome(14 days and 21 days)
研究者
Dr Manika Rawat
Teerthanker Mahaveer Dental College and Research Centre