The Effectiveness of Bupivacaine and Bupivacaine+Dexmedetomidine Combination in Transversus Abdominis Plane* Block
- Conditions
- Colorectal NeoplasmsColorectal Cancer
- Interventions
- Drug: bupivacain+dexmedetomidine
- Registration Number
- NCT06370949
- Lead Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
- Brief Summary
Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. Thus, TAP block is widely implemented in perioperative management of colorectal cancer patients.
Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries.
- Detailed Description
Transversus abdominis plane (TAP) block is an anesthesia method that provides somatic analgesia to the anterior and lateral abdominal walls. With the increasing use of ultrasound guidance during peripheral nerve blocks, trunk blocks such as the transversus abdominis plane (TAP) block are widely used for analgesia after abdominal surgery.
The advantages of TAP block include being less invasive than epidural analgesia, lower incidence of hypotension, and shorter hospital stay. Due to these advantages, TAP block has become a widely preferred method.
Researchers aimed to evaluate the analgesic effectiveness and duration of effect of dexmedetomidine added to bupivacaine in the TAP block applied in colorectal cancer surgeries. The study will be conducted in a tertiary oncology hospital in Turkey and 84 colorectal cancer patients will be included.
Recruitment & Eligibility
- Status
- NOT_YET_RECRUITING
- Sex
- All
- Target Recruitment
- 84
- colorectal cancer diagnosis
- undergoing colorectal cancer surgery
- allergic reaction to local anesthetics
- bleeding anomalies
- infection in TAP block area
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description bupivacaine Bupivacain Ultrasonography (USG) guided bilateral TAP block:20 ml %0,25 concentration bupivacain bupivacaine+dexmedetomidine bupivacain+dexmedetomidine Ultrasonography (USG) guided bilateral TAP block: 20 ml %0,25 concentration bupivacain+ 0.5 mcg/kg dexmedetomidine
- Primary Outcome Measures
Name Time Method Analgesic effectiveness of bupivacain and bupivacain+dexmedetomidine combination in colorectal cancer surgery postoperative day two Numeric Rating Scales of two groups in postoperative period. The numeric rating scale (NRS) is a pain screening tool, commonly used to assess pain severity at that moment in time using a 0-10 scale, with zero meaning "no pain" and 10 meaning "the worst pain imaginable"
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Turkey Dr.Abdurrahman Yurtaslan Ankara Oncology Train and Research Hospital
🇹🇷Ankara, Cankaya, Turkey