Prevalence and Outcome of Hypermetabolism in Initial Prevalence and Outcome of Hypermetabolism in Initial Phase of Intensive Care Unit Patient: a Prospective Observational Study

• Conditions: SIRS; Sepsis; Septic Shock

• Registration Number: NCT02002676
• Lead Sponsor: Nanjing University School of Medicine

Brief Summary

Patients in critical illness frequently present hypermetabolism， which can extremely increase the rest energy expenditure（REE）. We hypothesize that if we alleviate the extremely increased REE will improve ICU patients' outcome

Detailed Description

This study focuses on the early changes of REE of critical ill patients when they admitted to ICU.

Study Timeline

• Study First Submitted: 2013-11-26
• Study Start: 2013-12
• Study First Submitted QC: 2013-12-01
• Study First Posted: 2013-12-06
• Status Verified: 2014-06
• Primary Completion: 2014-06
• Study Completion: 2014-06
• Last Update Submitted: 2014-06-12
• Last Update Posted: 2014-06-13

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 62

Inclusion Criteria

• Older than 18 year.
• APACHEⅡ score≥8

Exclusion Criteria

• Hypercortisolism
• Thyroid disease
• Tracheoesophageal fistula
• FiO2>60 or PEEP>12cm H2O in mechanical ventilate
• Pregnancy

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mortality rate of 28 days	From ICU admission to 28th days of observation

Secondary Outcome Measures

Name	Time	Method
Incidence of Multiple Organ Dysfunction Syndrome（MODS）in 60 days	From ICU admission to 60th days of observation

Trial Locations

Locations (1)

Nanjing University School of Medicine; 🇨🇳 Nanjing, Jiangsu, China