A577-nm Pro -Yellow Laser In Treatment of Striae Rubra

Not Applicable

Recruiting

• Conditions: Striae Rubra

• Registration Number: NCT05598190
• Lead Sponsor: Al-Azhar University

Brief Summary

Stretch marks or striae are common skin condition occurring in both genders, but they are more prevalent among women. These are linear dermal scars that are accompanied by epidermal atrophy. They usually occur frequently in numerous physiological and pathological conditions, such as adolescent growth, pregnancy, obesity, Cushing disease, Marfan syndrome, and long-term systemic or topical steroid use. Decreased expression of collagen and fibronectin genes has also been associated with striae.

The pro-yellow laser systems can be used in a wide range of indications such as facial erythema, facial telangiectasia, port wine stain nevus, rosacea, poikilo derma civatte, and Becker's nevus

Some of these indications are clinical lesions in the vascular pattern; some are related to the factors that trigger vascularity, such as vascular endothelial growth factor (VEGF) in etiopathogenesis

Detailed Description

Not available

Study Timeline

• Study Start: 2022-09-15
• Status Verified: 2022-10
• Study First Submitted: 2022-10-25
• Study First Submitted QC: 2022-10-27
• Last Update Submitted: 2022-10-27
• Study First Posted: 2022-10-28
• Last Update Posted: 2022-10-28
• Primary Completion: 2023-09
• Study Completion: 2023-09

Recruitment & Eligibility

• Status: RECRUITING
• Sex: Female
• Target Recruitment: 18

Inclusion Criteria

• .Patients diagnosed with striae rubera. .Age groups: at any age. .Sex : ( females).

  • Co-operative patient

Exclusion Criteria

• Pregnancy .

  • Patient using drugs exacerbating stria as topical or systemic steroid, and patients using other forms of treatment for stria as topical tretinoin, emollients, glycolic acid peel and laser, because that might affect the result of our study.
  • Stria Alba.
  • Skin infection (viral, bacterial or parasitic).
  • Immunosuppressed patients or with history of malignancy or radiation therapy and chronic debilitating diseases and Cushing syndrome.
  • Hypersensitivity to light and intak of photosensitizing drugs.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
dermoscopic change of width of striae rubrae	1 year	dermoscopic photo for width of striae

Trial Locations

Locations (1)

AZHAR University Hospital; 🇪🇬 Assiut, Egypt