Comparison of the effect of depressive symptoms on the dose requirement during the start of anesthesia in patients undergoing surgery for cancerous and other non-cancerous conditions - A Prospective Observational Study
Not Applicable
- Conditions
- Health Condition 1: C00-D49- Neoplasms
- Registration Number
- CTRI/2020/08/027213
- Lead Sponsor
- JIPMER Intramural fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
1.Age > 18 years.
2.American Society of Anaesthesiologists (ASA) physical status I, II, and III.
3.Patients undergoing elective surgery for malignant and non-malignant non-neurological conditions.
Exclusion Criteria
1.Severe cardiovascular compromise or an ejection fraction of 20%.
2.Allergy to Propofol . 3. Modified Mallampatti Score 3 or more.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To compare the difference in propofol required for induction of anesthesia in patients undergoing surgery for malignancy versus those undergoing surgery for non-malignant conditionsTimepoint: Dose required to attain a BIS value between 50-60 at the time of induction
- Secondary Outcome Measures
Name Time Method To compare the amount of inotrope/ vasopressor/ anesthetic agent/ opioid required to restore the altered hemodynamic response associated with induction, laryngoscopy and intubation in patients undergoing surgery for malignancy versus those undergoing surgery for non-malignant conditions.Timepoint: 2,4,6,8,10 minutes;To record the hemodynamic response at the time of induction, laryngoscopy and intubation in patients undergoing surgery for malignancy versus those undergoing surgery for non-malignant conditions.Timepoint: 2.4.6.8.10 minutes;3.To compare the difference in propofol required for induction of anesthesia in patients undergoing surgery for malignancy with a PHQ-9 score more than 9 versus those undergoing surgery for malignancy with a PHQ-9 score less than or equal to 9.Timepoint: Dose required to attain a BIS value between 50-60 at the time of induction