Comparison the Effect of Remifentanil-Thiopental and Ketofol in major depressio

Phase 3

• Conditions: Major depressive disorder.; Major depressive disorder, single episode, unspecified; F32.9

• Registration Number: IRCT20210622051672N1
• Lead Sponsor: Arak University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 30 August 2021

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

All patients with major depressive disorder candidates for Electro Convulsive Therapy referred to Arak Amirkabir Hospital
All patients candidates for Electro-Convulsive Therapy who have signed an informed consent form to enter the study
Patients in the age range of 18 to 60 years
Patients with a BMI in the range of 20 to 30
Patients with major depressive disorder who do not have another psychiatric illness at the same time

Exclusion Criteria

Pregnancy
Breastfeeding
sensitivity to Remifentanil or Thiopental or Propofol
taking anticonvulsant drugs
recent CVA or MI history
history of underlying diseases of the heart, lungs, kidneys and liver

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Mean Arterial Pressure. Timepoint: Beginning and the end of recovery. Method of measurement: Monitor.;Pulse Rate. Timepoint: Beginning and the end of recovery. Method of measurement: Monitor.;Pulse oximetry (SpO2). Timepoint: Beginning and the end of recovery. Method of measurement: Monitor.;Satisfaction score. Timepoint: After recovery. Method of measurement: questionnaire.;Agitation Score. Timepoint: After recovery. Method of measurement: questionnaire.;Duration of seizures. Timepoint: beginning and the end of seizures. Method of measurement: Minutes with chronometer.;Duration of recovery. Timepoint: Beginning and the end of recovery. Method of measurement: Chronometer.