Effects of reduced whole body temperature on DNA damage in new born babies having birth asphyxia
Not Applicable
Completed
- Conditions
- Health Condition 1: null- Term new borns with perinatal asphyxia
- Registration Number
- CTRI/2011/10/002094
- Lead Sponsor
- JIPMER
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 120
Inclusion Criteria
Inborn babies with
(1,2,3 + Any one of 4 )
1.Gestational, age >= 37 weeks
2.ABG(umbilical cord or 1st postnatal hour
pH <=7 or Base deficit >= 12meq
3.APGAR <=6 at 5 min
4.Any one of the following
i.Evidence of encephalopathy
(THOMPSON SCORE >5)
ii.Evidence of fetal distress
iii.Assisted ventilation for at least 10 min after birth
iv.Evidence of any organ dysfunction
v.History of acute perinatal event- intrapartum fetal distress, cord prolapsed, placental abruption ,uterine rupture, maternal trauma, cardiac arrest
Exclusion Criteria
i. Infants >6 hours of age at the time of randomisation
ii. Major congenital abnormalities
iii. If the baby does not establish spontaneous
respiration by 20 minutes
iv. Out born babies
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method