Management of Perioperative Pain Using Erector Spinae Plane Block in Open Microscopic Lumbar Surgery
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 40
- 试验地点
- 2
- 主要终点
- Pain score at recovery, 30mins, 1, 2, 4, 8,12, 24 hours post-surgery
研究概览
简要总结
The aim of this study is to compare patients receiving bilateral erector spinae block with ropivacaine vs control group in terms of pain score, total opioid consumption, hemodynamic changes intraoperatively, length of hospitalisation , time to ambulation post surgery and quality of recovery.
详细描述
Most open spine surgery exacts a high degree of postsurgical pain due to the incision and muscle dissection of the vertebra. The postoperative pain control and early mobilization improve the quality of the surgical care. Inadequate pain relief might result in perioperative morbidity, resulting in prolonged hospital stays.
Erector spinae plane block (ESPB) is an interfascial plane block where local anaesthetic is injected in a plane preferably below the erector spinae muscle. It can provide thoracic, abdominal, and even some lower extremity analgesia. It was also theorised that erector spinae plane block can reduce opioid use and provide analgesia for lumbar surgery. The financial cost that is saved by reducing the length of hospital stay, perioperative morbidity will warrant the use of erector spinae plane block in patients undergoing lumbar spine surgery.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age 18-75
- •Patients with Glasgow Coma Scale of
- •American Society of Anaesthesiologists (ASA) Physical Status Classification I - II patients
- •Scheduled for elective, open microscopic lumbar surgery (less than 3 levels) under general anesthesia.
排除标准
- •Cognitive impairment
- •Patient refusal
- •Weight<50kg, >120kg
- •Allergy to local anesthesia
- •Alcohol/ drug abuse
- •Renal failure or liver failure
- •Coagulopathy/thrombocytopenia
- •Chronic pain with chronic opioid usage
- •Ischemic heart disease
研究组 & 干预措施
Control group
Pre incision of 0.375% ropivacaine 10ml local infiltration will be given.
干预措施: Skin infiltration LA (Procedure)
Ropivacaine group
Bilateral erector spinae plane block (0.375% 20ml ropivacaine on each side + adrenaline 1:200,000) pre incision.
干预措施: Erector spinae plane block (Procedure)
结局指标
主要结局
Pain score at recovery, 30mins, 1, 2, 4, 8,12, 24 hours post-surgery
时间窗: 24 hours
Measure by numerical rating scale (minimum 1-least pain, maximum 10-most painful)
Total opioid consumption intraoperative
时间窗: 48 hours
Measure by total dose consumed (in milligram)
Total opioid consumption post-operative
时间窗: up to 72 hours
Measure by total dose consumed (in milligram)
Timing of first rescue dose of iv morphine
时间窗: up to 24 hours
Post operation till time requiring first dose of iv morphine
次要结局
- The quality of recovery score (QoR)-15 questionnaire at 24 hours post-operation(24 hours)
- Length of hospital stays(up to 1 week)
- Time to ambulation after surgery(up to 1 week)
- Hemodynamic changes intraoperative(Intraoperative period)