Comparison of Erector Spinae Plane Block and Pecto-Intercostal Facial Plane Block For Enhanced Recovery After Sternotomy in Adult Cardiac Surgery
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 60
- 试验地点
- 1
- 主要终点
- Total dose of fentanyl consumption
研究概览
简要总结
The current study is designed to compare the perioperative analgesic efficacy of Erector spinae plane block (ESPB) and Pecto-intercostal-fascial plane block (PIFB) in adults undergoing cardiac surgery via median sternotomy.
The primary outcome measure will be the analgesic effectiveness of both blocks in median sternotomy pain, while the secondary outcome measures will be time to extubation, and length of intensive care unit stay.
详细描述
The patients will undergo the same preoperative preparation, intraoperative monitoring, and anesthetic technique. Fentanyl (2 μg/kg) will be given with induction of anesthesia, and additional increments of fentanyl 2 μg/kg will be administered if mean arterial blood pressure or heart rate rise in response to stressful surgical stimuli greater than 20% above baseline.
All surgeries will be performed through median sternotomy, with the same cardiopulmonary bypass and myocardial protection technique. At the end of surgery, all anesthetics will be discontinued, and patients will be transferred to the ICU where they will be committed to a mechanical ventilator.
the two blocks will be performed using Linear -Array ultrasound transducer probe (SONOSITE M-TURBO). After standard chest skin disinfection, the transducer will be covered with a sterile sleeve.
he two blocks will be performed using Linear -Array ultrasound transducer probe (SONOSITE M-TURBO). After standard chest skin disinfection, the transducer will be covered with a sterile sleeve.
Ultrasound guided Pecto-intercostal- fascial plane block:
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •adult patients of either sex
- •aged 18-50 years
- •undergoing elective cardiac surgery via median sternotomy
排除标准
- •refusal to participate,
- •urgent cardiac surgery
- •local infection of the skin at the site of needle puncture
- •allergy to bupivacaine, coagulation disorders
- •clinically significant liver or kidney disease, heart failure, moderate to severe pulmonary hypertension
- •extubation is intentionally planned to be delayed.
研究组 & 干预措施
Group (P)
干预措施: Bupivacain (Drug)
Group (P)
干预措施: Ultrasound guided Pecto-intercostal- fascial plane block (Procedure)
Group (E)
干预措施: Ultrasound guided erector spinae plane block (Procedure)
Group (E)
干预措施: Bupivacain (Drug)
结局指标
主要结局
Total dose of fentanyl consumption
时间窗: after 24 hours postoperative
Analgesic effectiveness of both blocks in median sternotomy pain
次要结局
- ICU Length of stay(after 48 hour postoperative)
- time to extubation(after 1 hour of removal of endotracheal tube)