Functional Behavior-based Cognitive-Behavioral Therapy for Obsessive Compulsive Behavior in Children With Autism Spectrum Disorder: A Randomized Controlled Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 37
- 试验地点
- 2
- 主要终点
- Change in Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS)
研究概览
简要总结
Individuals with high functioning autism spectrum disorder (ASD) frequently experience obsessions and/or compulsions that are similar to those specified in Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5) criteria for obsessive compulsive disorder (OCD). However, little research exists on effective interventions for OCD symptoms (referred to as OCBs) in ASD. In a randomized controlled trial, a manualized functional behavior-based cognitive-behavior therapy (Fb-CBT) consisting of traditional CBT components (psychoeducation and mapping, cognitive-behavioral skills training, exposure, and response prevention) as well as function-based behavioral assessment will be evaluated. Participants will be assigned randomly to Fb-CBT or treatment as usual (TAU). Primary and secondary outcome measures will be used to evaluate the efficacy of the treatment, and will be administered at pre and post-intervention as well as six month follow-up.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Outcomes Assessor)
入排标准
- 年龄范围
- 7 Years 至 13 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Previous diagnosis of ASD
- •Presence of OCBs as defined by Sameness, Ritualistic and Compulsive subscales on the RBS-R
- •a Full Scale IQ (WISC-IV; Wechsler, 2004) ≥ 70
- •parent indicated no planned change in child medication during the study (unless the physician deemed the change medically necessary)
排除标准
- •participation in treatment for anxiety
- •participation in treatment for repetitive behaviour
- •participation in treatment for intensive behavioural intervention
结局指标
主要结局
Change in Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS)
时间窗: Assessment occurred at baseline and 2 weeks following end of treatment
A 10-item, semi-structured interview used to assess symptom severity for children ages 6 through 17 years. Each item is rated on a 5-point ordinal scale from 0 (none) to 4 (extreme)' For the purpose of this study, only the 5-item Compulsion score was used pre and post-treatment.
Change in Repetitive Behavior Scale (RBS_SCR)
时间窗: Assessment occurred at baseline and 2 weeks following end of treatment, as well as at follow-up (6 months following the cessation of treatment)
The RBS is a 43-item parent rating measure of repetitive behavior. It is comprised of a four-point Likert scale ranging from (0) behavior does not occur, to (3) behavior occurs and is a severe problem . The RBS\_SCR scale specifically focusses on the assessment of sameness, compulsive, and ritualistic behaviors
次要结局
- Change in The child Obsessive-Compulsive Impact Scale-Revised (COIS-R)(Assessment occurred at baseline and 2-weeks following the end of treatment, as well as at follow-up (6 months following the cessation of treatment))
- Parent OCB Rating Scale.(Scale was completed by parents at baseline, each day throughout the 9-week treatment period, and at follow-up (6 months following the cessation of treatment))
- Change in Repetitive Behavior Scale 100 (RBS_100)(Assessment occurred at baseline and 2 weeks following the end of treatment, as well as at follow-up (6 months following the cessation of treatment))
研究者
Tricia Vause
Associate Professor
Brock University