Measurement of Blood Loss Using Electrical Impedance Tomography
试验速览
- 阶段
- 不适用
- 入组人数
- 15
- 试验地点
- 4
- 主要终点
- Change in chest electrical impedance due to blood loss.
研究概览
简要总结
The project focuses on the possibility of detecting blood loss using electrical impedance tomography. Based on previous animal experiments, it was found that the bolus of saline significantly affects the signal of chest bioimpedance. It is assumed that blood loss of a similar volume will cause a similar signal change with the opposite trend. The aim of this project is to determine whether there is a significant change in the thoracic electrical impedance tomography signal when blood loss is caused by voluntary blood donation.
详细描述
Electrical impedance tomography is a bedside method of ventilation monitoring. The bioimpedance of the tissue depends, among other things, on its blood content. The area of the chest and especially the lungs is a heavily perfused tissue, which also serves as one of the reservoirs of blood in case of blood loss. It is therefore possible that blood loss will be visible on chest bioimpedance relatively soon.
The study will be performed on voluntary blood donors. Blood loss of 450 mL will be caused by the collection of donated blood. During blood collection at the transfusion department, thoracic bioimpedance will be measured using electrical impedance tomography. The resulting signal change will then be analyzed to determine the possibility of detecting and measuring blood loss using electrical impedance tomography.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •voluntary blood donation
排除标准
- •standard exclusion criteria for voluntary blood donation based on the transfusion station protocol
- •standard exclusion criteria for electrical impedance tomography according to the manufacturer
结局指标
主要结局
Change in chest electrical impedance due to blood loss.
时间窗: Time frame of one voluntary blood donation process (15 min)
A change in the electrical impedance of the chest of a voluntary blood donor caused by a blood donation.
次要结局
未报告次要终点