The association between Neuropeptide Y (NPY) peptide/ Gut Hormones and skeletal health

Not Applicable

Completed

• Conditions: Obesity; The degree of bone loss in obese subjects following massive weight loss; An impact of bariatric surgery and gut hormones on bone mass; Musculoskeletal - Other muscular and skeletal disorders; Metabolic and Endocrine - Other metabolic disorders; Diet and Nutrition - Obesity

• Registration Number: ACTRN12613000188730
• Lead Sponsor: A/Prof Jacqueline Ruth Center

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2013-02-18
• Study Completion: 2015-11-15
• Last Update Posted: 21 July 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

1) BMI> 40 or BMI> 35 with medical complication from obesity
2) Presence of obesity for the last 5 years, which has persisted despite multiple attempts with other weight loss measures
3) Patient who is either undergoing bariatric surgery or who is enrolled into the intense medical management plan with the aim to lose significant amount of weight.
4) Willingness and ability to comply with the protocol of the study
5) Willingness to provide written informed consent

Exclusion Criteria

1) Pregnancy or patient planning pregnancy in next 2 years of the study
2) Women, who are within 5 years after the onset of menopause
3) Intake of medications known to affect bone mineral density (BMD)
4) Active alcohol or drug dependency
5) Active psychosocial or psychiatric problem that would make adherence to the protocol difficult

Study & Design

• Study Type: Observational
• Study Design: Not specified