Weight loss surgery and changes in bone marrow fat and bone mass.
- Conditions
- ObesitySurgery induced weight lossOsteoporosis
- Registration Number
- NL-OMON23764
- Lead Sponsor
- Academic Medical Center, Amsterdam
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Pending
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
* Female sex
* Age: 18-55 years50 years and older
Exclusion Criteria
* Contraindications to MRI scanning
* Use of bone-modifying or adipose tissue-modifying drugs
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method * Vertebral bone marrow fat fraction measured by QSCI<br /><br>* Vertebral bone mineral density measured by QCT
- Secondary Outcome Measures
Name Time Method Bone turnover markers (CTx, P1NP, osteocalcin), 25-hydroxy vitamin D, parathyroid hormone, calcium, albumin, phosphate, alkaline phosphatase, creatinin, complete blood count (CBC), reticulocytes, leptin, adiponectin