CTRI/2023/11/059391
Not yet recruiting
Phase 2
To compare the efficacy of Topical Beta blocker (0.5% Timolol Maleate) and Ultrapotent Corticosteroid (0.05% Clobetasol Propionate) in the treatment of superficial infantile Capillary Hemangioma (ICH) via Randomized Control Trial: A Single Centre Pilot Study - Nil
All India Institute of Medical sciences, Raebareli, U.P.0 sites0 target enrollmentStarted: TBDLast updated:
Overview
- Phase
- Phase 2
- Status
- Not yet recruiting
- Sponsor
- All India Institute of Medical sciences, Raebareli, U.P.
Overview
Brief Summary
No summary available.
Study Design
- Study Type
- Interventional
Eligibility Criteria
Inclusion Criteria
- •All children less than \<36 months of age having clinical and color Doppler\-proven infantile capillary hemangioma (ICH).
- •1\. Superficial ICH on Doppler, including mucosal surfaces, and ulcerated ICH
- •2\. Size of lesion \> 1\.5 Cm
- •3\.No H/O prior tt for ICH
- •4\. Patients at risk of adverse effects of systemic beta\-blockers like Cardiac arrhythmias, first\-degree heart block; recovered pts of cardiogenic or hypotensive shock, sinus bradycardia, Asthma, history of hypoglycemia, birth weight \< 2500 g would be included.
Exclusion Criteria
- •1\. Age at the time of enrolment is \>36 months
- •Dermal invasive ICH
- •2\. Life\-threatening ICH
- •3\. Persistent arrhythmias, wheezing, heart failure
- •4\. Associated Visceral vascular (liver/ renal/brain) lesions
- •5\. Patients Having Raynaud phenomena
- •6\. Bradycardia below the age\-specific range for normal
- •7\. Low blood pressure according to age\-specific ranges for normal
- •8\. known case of Pheochromocytoma
- •9\. Breast\-feeding mothers who are on treatment with oral propranolol
Investigators
Similar Trials
Recruiting
Phase 3
Investigating the effectiveness of beta-blocker on hypermetabolic response in adult patients due to acute burnsIRCT20230301057584N1Bandare-abbas University of Medical Sciences90
Completed
Phase 3
Effect of cryotherapy and oral antihistamine in treatment of Alopesia AreataIRCT20210404050843N1Esfahan University of Medical Sciences48
Not yet recruiting
Not Applicable
Conparision of transdermal patch beta1 blocker or oral medication on Coronary Computed Tomography AngiographyIschemic heart deseseJPRN-UMIN000039128Kansai Medical Hospital100
Completed
Not Applicable
Comparison of the effects of two beta blockers, bisoprolol and carvedilol on chronic heart failure Bisoprolol Improvement Group for Chronic Heart Failure Treatment Study in Dokkyo Medical University:BRIGHT-DChronic Heart FailureJPRN-UMIN000011261Dokkyo Medical University Department of Cardiovascular Medicine75
Recruiting
Not Applicable
The study of the usefulness of beta-blocker for hypertensive patients with persistent atrial fibrillation combined with reduced cardiac functiohypertensive patients with persistent atrial fibrillation combined with reduced cardiac functionJPRN-UMIN000001848ihon University School of Medicine20